Ok I've got two from the episode Trading Faces.
(Presenting his machine to the class.)
"It translates your thoughts and feelings into notes and rhythems. And so without further adeu. I now present the musical stylings of my brain."
(Turns on the radio.) (Plays "Discovery Channel" )
(Everyone in the class gapes at Jimmy for a moment then starts bursting out laughing)
"Wow Jimmy. I didn't know you were that pervertive!"
"WTF???" (looks at his machine)
Director: "CUT!! Who put that song in the CD player?!?"
"Cindy, you weren't supposed to play that song!"
"Sorry. Couldn't resist."
OK maybe the next one will be funnier...
(Jimmy and Cindy are about to get their minds dumped in the machine)
"Ok listen up here. When our brains are uploaded. All of our memories will appear on that screen. You three have to decide what belongs to who. Don't give Cindy my astounding ability to create and build pioneering technologies, Okay?"
"Oh yeah, like I'd want to invent toilet in a brief case."
"Hey, hey that could have been an invaluable excessory for the traveling business man!"
"Carl, throw the switch and shut them up."
(Carl throws the switch and Jimmy and Cindy get electricuted.)
"Ow!!! Neutron! What the heck are you trying to pull? Are you trying to get me killed?"
"Ow!! Shut it Vortex! Carl that was the wrong switch!"
"Sorry!" (Pulls the other switch)
(Jimmy and Cindy are unconscious and get their minds dumped.)
"Hey who wants to mess with them and switch some of their memories!"
"Boy you got to be crazy! I'm in."
Director: Oh no you don't! Get them back in their right heads now! This wasn't even supposed to happen in the first place.
Ok maybe my ideas weren't that funny...